1,3-Butadiene

CAS Number: 106-99-0

SERIOUS
health hazard

MODERATE
health hazard

FEW OR NO
health hazards

0 79

80 89

90 100

Sources of exposure:

Industrial uses

Description:

1,3-Butadiene is a gaseous hydrocarbon primarily used in the industrial production of synthetic rubber and plastics.

Health concerns:

Cancer

Known or suspected to increase cancer risk in humans.

Reproductive Toxicity

May alter hormone function and harm reproduction.

Developmental Toxicity

May impact fetal development and birth outcomes.

Genotoxicity

May cause mutations or damage DNA in cells.

Neurotoxicity

May impact brain function or development.

Respiratory Toxicity & Asthmagens

May damage the lungs or trigger asthma.

Ecotoxicity

May be toxic to ecosystems and wildlife.

Contaminants:

benzene
toluene
styrene

Banned/restricted lists:

European Commission Annex II prohibited substances. Government of Canada. List of Ingredients that are Prohibited for Use in Cosmetic Products.

References

HOW MILLION MARKER SCORES CHEMICALS

Million Marker's Ingredient Hazard Scoring uses multiple chemical databases and a science-backed scoring system to compute hazard scores for thousands of chemicals found in consumer products and listed on ingredient labels.

We identified key chemicals based on a database compiling dozens of authoritative sources, screening tools, and QSAR models.

Hazard scores within 11 different health categories (carcinogens, endocrine disruptors, reproductive toxicants, developmental toxicants, genotoxicity, neurotoxicity, organ system toxicity, immunotoxicity, respiratory toxicity, skin/eye/respiratory irritants, and ecotoxicity).

They are weighted based on several factors, including strength of evidence for adverse impacts in humans, severity, and potential contamination.